Biophysics and Opto-Nanobiotechnologies

Biophysics and Opto-Nanobiotechnologies


Bortolozzi Mario, Mammano Fabio, Romanato Filippo, Sada Cinzia, Zaltron Annamaria


Borile Giulia, Gazzola Enrico, Imran Saima, Mafakheri Erfan, Massari Michele, Rossi Roberto, Ruffato Gianluca, Carrer Andrea, Mazzocca Matteo, Urzi Alessia

PhD students

Buratto Damiano, Filippi Andrea, Gintoli Michele, Zamboni Riccardo

Research Activity

Line 1: Prof. Fabio Mammano uses biophysical and optical techniques, as well as computational models, to analyze the structure and function of membrane proteins, called connexins, expressed in the inner ear and the skin. Mutations of these proteins cause genetic deafness and dermatologic syndromes. Prof. Mammano is also interested in photodynamic therapy and Ca2+ signals in the tumour microenvironment.

Line 2: Prof. Mario Bortolozzi biophysical approach involves electrophysiology, optical microscopy and numerical simulations to answer relevant biomedical questions, in particular related to the molecular pathogenesis of peripheral neuropathies. Prof. Bortolozzi is also interested in developing computational models for the study of Ca2+ dynamics, as well as of other important second messengers in living cells. 

Line 3: Prof. Filippo Romanato uses nanofabrication techniques for the development of complex microscopic, microfluidic and sensory systems. The group has experience in the design and development of nanostructures using lithographic and nanofabrication techniques on simple or composite materials. The structures are then characterized and studied to verify their functional properties, which, as in the case of metamaterials, can be very sophisticated. The nanostructures are then integrated into miniaturized devices: biosensors, microscopic and nanoscopic systems, medical systems. The developed technologies are applied to the study of exosome, genetics, and bacterial revelation.

Line 4: Prof. Cinzia Sada studies insulators and the modification of their local and bulk properties  for application in integrated optics, photonics and opto-microfluidics. Particular attention is devoted to the preparation, characterization and modelling of opto-microfluidic platforms in lithium niobate crystals and similar materials for optical sensing, optical manipulation and sorting of micron-scale targets dispersed in microfluidic channels.